Endocrine Abstracts

Introduction: Turners’ syndrome (TS) affects one in 2500 live births. Multiple comorbidities affect TS patients and recommendations for long-term management advocate annual review with a ‘checklist’ approach. This audit of current practice of a specialist TS clinic aims to identify gaps in patients’ management.Methods: A checklist of recommendations for health screening based on the National Turner’s Syndrome Guidelines was devel...

We report the case of a 59-year-old male who presented complaining of several weeks of tiredness, poor appetite and dizziness on standing. He had been treated with flucloxacillin by his GP for otitis externa one week earlier.In 1982, he was diagnosed with nasopharyngeal carcinoma in Hong Kong, which was treated by radical dissection and radiotherapy.On examination, his standing and lying blood pressure were 150/100 and 110/90 respe...

Introduction: Smokers around the globe commonly report increased body weight after smoking cessation as a major factor that interferes with their attempts to quit. In addition, numerous controlled studies in both humans and rodents have reported that nicotine exerts a marked anorectic action. Nicotine’s effects on energy homeostasis have been mostly pinpointed in the central nervous system, but the molecular mechanisms controlling its action are still not fully understood...

Increased hypothalamic-pituitary-adrenal (HPA) activity in the fetus is a consistent event across different animal species, including the human. Fetal HPA activation contributes both to maturation of organ systems required for extra-uterine life and provides the trigger for the birth process. Precocious activation of the fetal HPA axis, for example in response to an adverse intrauterine environment or periconceptual undernutrition may result in increased incidence of preterm b...